The plane wreckage is around 300 yards away from the end of the runway surrounded by emergency vehicles
Mount Pleasant Police tell News 2 that two people were killed when the plane crashed.
Authorities say the NTSB will be handling the crash investigation, they are reportedly en route.
The Mount Pleasant Regional Airport is currently closed.
Stay with News for the latest on this developing story.
Crews are responding to Mount Pleasant Regional Airport on reports of a plane crash.
Sources tell our TV Partner News 2 that the plane was possibly a Cessna and that there may be casualties. Stay with News Radio 94.3 WSC for the latest on this developing story.